Author name: Datharsis

The hidden language of omics data

Omics data allow us to decipher the different languages of biology: that of DNA, RNA, proteins, and metabolites. Each layer—genomics, epigenomics, transcriptomics, proteomics, and metabolomics—provides an essential piece for understanding biological systems in all their complexity. At Datharsis, we analyze and integrate this information to transform biomedical data into explainable and applicable knowledge.

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Recommendations for sampling design for a solid statistical analysis

A brilliant data analysis does not compensate for a poorly designed experiment. The basis of any reliable knowledge lies in experimental design, and this is supported by three universal principles: Randomization (to avoid hidden biases), Replication (to confirm that results are not accidental), and Blocking (to isolate and neutralize known external variations). Investing in a robust design is the best guarantee that your statistical analysis will produce useful and secure knowledge.

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Sparse PCA and biomarkers: understanding more, assuming less

Which variables should you actually interpret in a statistical model?
In this article, we explain how Sparse PCA (SPCA) — and a new corrected version — can help you identify key variables, such as biomarkers, without losing interpretability. A practical approach from biostatistics for projects with lots of data and little certainty.

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